Manganese-Enhanced MRI: Biological Applications in Neuroscience
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چکیده
منابع مشابه
Manganese-Enhanced MRI: Biological Applications in Neuroscience
Magnetic resonance imaging (MRI) is an excellent non-invasive tool to investigate biological systems. The administration of the paramagnetic divalent ion manganese (Mn(2+)) enhances MRI contrast in vivo. Due to similarities between Mn(2+) and calcium (Ca(2+)), the premise of manganese-enhanced MRI (MEMRI) is that the former may enter neurons and other excitable cells through voltage-gated Ca(2+...
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متن کاملManganese-enhanced MRI of mouse heart during changes in inotropy.
Recently the dual properties of manganese ion (Mn(2+)) as an MRI contrast agent and a calcium analogue to enter excitable cells has been used to mark specific cells in brain and as a potential intracellular cardiac contrast agent. Here the hypothesis that in vivo manganese-enhanced MRI (MEMRI) can detect changes in inotropy in the mouse heart has been tested. T(1)-weighted images were acquired ...
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ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2015
ISSN: 1664-2295
DOI: 10.3389/fneur.2015.00161